Yes, AMI is safe. The radio signal from the meter falls well below the threshold set by the Federal Communications Commission for healthy and safety standards and is not a health concern. In fact, everyday devices found inside the home, such as microwave ovens, have significantly greater radiofrequency exposure than AMI meters.
The three factors that contribute to RF exposure are signal duration, RF energy, and distance from source. AMI meters transmit a signal for a fraction of a second, emits much less RF energy than common household items, and is generally located away from the house at the meter box.